For HIV.
Brand Name(s): Juluca
Generic Name: Dolutegravir/Rilpivirine
Instructions
Swallow the medicine without crushing or chewing it.
Take the medicine with a meal.
Swallow with a full glass (8 oz) of water unless your doctor gives you different instructions.
Ask your doctor if any of your medicines need to be taken at the same time.
This medicine will work best if you take it at about the same time every day.
Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.
Store in original bottle, tightly closed.
Keep the desiccant (drying) packet in the bottle and keep the bottle closed tightly.
This medicine does not stop the spread of viruses that are passed through the blood or during sex.
Always use condoms during sex.
Do not share needles or other personal objects such as shavers or toothbrushes.
If you take sucralfate, antacids or other products containing calcium, aluminum, magnesium, or iron, these should be taken 6 hours before or 4 hours after this medicine.
If you take supplements containing iron or calcium, these supplements may be taken at the same time as this medicine with food.
If you are taking medicines used to reduce stomach acid (H2 receptor blockers), take them at least 12 hours before or 4 hours after this medicine.
Do not take proton pump inhibitors (PPIs), such as omeprazole or lansoprazole, to reduce stomach acid while taking this medicine.
Tell your doctor if you have severe or persistent sweating, diarrhea or vomiting. These can increase your risk of a serious side effect.
It is important that you keep taking each dose of this medicine on time even if you are feeling well.
If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.
Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.
Keep all appointments for medical exams and tests while on this medicine.
Cautions
Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.
Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.
This medicine may affect areas where fat is stored in the body. This may change your body shape.
Do not use the medication any more than instructed.
Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.
This medicine passes into breast milk. Because breast milk may transmit HIV, ask your doctor before breastfeeding.
Do not take St. John's wort while on this medicine.
Do not share this medicine with anyone who has not been prescribed this medicine.
Always refill this medicine before it runs out.
Side Effects
The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.
- diarrhea
- headaches
- red, burning, or itchy skin
Call your doctor or get medical help right away if you notice any of these more serious side effects:
- cough that does not go away
- swelling of the face, mouth, tongue, or throat
- bulging eyes
- fainting
- flu-like symptoms
- numbness or tingling in hands and feet
- severe or persistent headache
- fast or irregular heart beats
- irritability
- signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
- mood changes
- loss of movement anywhere on the body
- muscle weakness
- joint or muscle pain
- nervousness
- shortness of breath
- sore throat
- difficulty speaking
- slurred speech
- suicidal thoughts
- difficulty swallowing
- swelling in the neck or throat
- difficulty adjusting to changes in temperature
- unsteadiness while walking
- blurring or changes of vision
- weight gain
A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.
Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.
IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all there is to know about it. Your doctor or pharmacist may give you other documents about your medicine. Please talk to them if you have any questions. Always follow their advice.
There is a more complete description of this medicine available in English. Scan this code on your smartphone or tablet or use the web address below. You can also ask your pharmacist for a printout. If you have any questions, please ask your pharmacist.
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More information about DOLUTEGRAVIR/RILPIVIRINE - ORAL
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Conditions of Use: The information in this database is intended to supplement, not substitute for the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express Terms of Use.